zurück

Genomics and Epigenomics of Psychiatric Disorders

medizinischegenetik 1 - 2020
Wissenschaftliche Koordination: Markus Nöthen
Kurze Zusammenfassung
Despite its high frequency and many decades of researc, the biological basis of psychiatric disease remains poorly understood. This has implications in terms of treatment, with many currently available therapies showing limited efficacy or, in the case of drug therapy, adverse side effects. For many years, researchers have hoped that breakthoughts in the biological understanding of psychiatric disease could be achieved through the use of genetic approaches. Even early descriptions of psychiatric disorder cases reported a familial occurance.
Schwerpunkt Bild
Bildcollage: GfH

Inhalt

Out of the lab and into the clinic: steps to a pragmatic new era in psychiatric genetics
Nöthen Markus M. Download PDF

Insights into the genomics of affective disorders
Forstner Andreas J., Hoffmann Per, Nöthen Markus M., Cichon Sven Download PDF

Update on the genetic architecture of schizophrenia
Degenhardt Franziska Download PDF

Genetic and epigenetic findings in anorexia nervosa
Hirtz Raphael, Hinney Anke Download PDF

Clinical genetic testing and counselling in autism spectrum disorder
Freitag Christine M., Haslinger Denise, Yousaf Afsheen, Waltes Regina Download PDF

Polygenic scores for psychiatric disease: from research tool to clinical application
Andlauer Till F.M., Nöthen Markus M. Download PDF

Brain imaging genomics: influences of genomic variability on the structure and function of the human brain
Mühleisen Thomas W., Forstner Andreas J., Hoffmann Per, Cichon Sven Download PDF

A Review of epigenetics in psychiatry: focus on environmental risk factors
Keverne Jessica, Binder Elisabeth B. Download PDF